Timetables & Descriptions

 

 

 

The following is a listing of all courses offered by or in collaboration with the IMS. Please note that not all courses are offered each year. Students who add courses which have “TBA” offerings may have their registrations cancelled if the course ultimately is not offered.

2021-22 COURSE UPDATES IN PROGRESS:  Enrollment in IMS Courses for the 2021-22 academic session will open in mid-July.  We are currently confirming which courses are to be offered and in which  term, as well as start dates, days/times, and delivery method  The information below will be updated once that information is available, at which point ACORN requests will be accepted. Please follow the instructions for courses requiring instructor permission.

Please note the following information regarding course weighs:

Quarter-credit course codes (0.25 FCE) end in H (This applies to IMS modular courses in the MSC1100 series only.) 
Half-credit course codes (0.5 FCE) end in H.
Full credit course codes (1.0 FCE) end in Y.

For questions about course enrollment please contact Sobiga

Building Legend:
BL – Claude T. Bissell Building, 140 St. George Street
CAMH – Centre for Addiction and Mental Health, College St. Site: 250 College St.
MaRS TMDT – MaRS Toronto Medical Discovery Tower: 101 College St.
MSB – Medical Sciences Building: 1 King’s College Cir.
PB – Leslie L. Dan Pharmacy Building: 144 College St.
PMH – Princess Margaret Cancer Centre: 190 Elizabeth St.
TGH – Toronto General Hospital: 200 Elizabeth St.

IMS MSc and PhD Modular Courses

Students enrolled in MSC1010/11H can fulfill their two x 0.25 (FCE) modular course requirement (for those enrolled in September 2020) through modules offered by the Translational Research Program. Please refer to this link for information. Students in the Translational Research Program may also enroll in two IMS modular courses. 

Note: For the 2020 Fall term, IMS students may only take TRP modular courses.

Other than the above, IMS modular courses are not available to non-IMS students nor are they available for credit to IMS students enrolled in MSC1010/1011Y, who will complete their two-module requirement as part of that course and who must enroll in the modules via Quercus.

 

 

MSC1100H (0.25 FCE): Success in Graduate School: a Professional Development Module for MSc Students (Credit/No Credit) - Session: Winter 2022

Instructor: Pamela Plant 

Session Offered: 20221
Start Date: January 14, 2022 - February 18, 2022 (6 sessions) Time: 3:00 - 5:00 pm, Location: Online

Description: MSc graduates from the IMS continue their education in PhD programs and professional schools, volunteer/intern, or enter the job market. As graduate students they become familiar with an area of research, learn technical skills as applied to their research project and develop their communication and critical thinking skills. This course focuses on creating a healthy student-supervisor relationship, project and time management, developing transferable skills, and building a professional network. Each session will feature an interactive presentation, inclass activities and peer evaluations. Students will be expected to read resources provided and prepare materials before each class. Complementing the course will be a series of Friday afternoon interactive career development panels and networking events.

MSC1101H (0.25 FCE): Success After Graduate School: a Professional Development Module for PhD Students (Credit/No Credit) - Session:  Fall 2021

Instructor: Pamela Plant

Session Offered: 20219
Start Date: October 22, 2021 - November 26, 2021 (6 sessions), Time:  3:00 pm - 5:00 pm, Location: Online

Description: PhD graduates from the Institute for Medical Sciences (IMS) continue to be employed as professors and scientists in research institutes but increasingly are finding jobs in other sectors of the economy. This course module is designed to enable PhD students to assess and develop their leadership and transferable skills in order to take better advantage of the opportunities available to them in academia and beyond. Each session will feature an interactive presentation and in-class activities. Complementing the course will be IMS Connects, a series of Friday afternoon interactive career development panels and networking events designed for IMS students featuring alumni working in various sectors.

MSC1102H (0.25 FCE): Psychiatric Implications of Traumatic Brain Injury (Credit/No Credit) - Session: tbd

Instructor: Shree Bhalerao

Session Offered: tbd
Start Date: tbd, Location: Online

Description: Traumatic brain injury (TBI) has become very popular in the fields of neurology, neurosurgery, psychiatry and in the media. Most studies suggest that fifty percent of TBIs are not reported and thus go untreated. Despite this, most people are unaware that the risk for psychiatric disorders can double following a TBI. Thus, a team of two psychiatrists and a neuroscientist will present a module on the psychiatric sequalae following TBI. The course will xamine six main psychiatric issues associated with TBI: depression, anxiety, addiction, agitation, aggression, and the stigma associated. Each session will utilize didactic, interactive, multimedia elements and group activities to explore diagnostic, neurological, and management issues associated with TBI

MSC1103H (0.25 FCE): Knowledge Translation (Credit/No Credit) - Session:  Winter 2022

Instructor: Katie Dainty

Session Offered: 20221

Dates: January 26, 2022 - February 23, 2022, Time: 9:30 am - 11:30 am, Location: Online

Description: CIHR defines Knowledge translation (KT) as “the exchange, synthesis and ethically-sound application of knowledge—within a complex system of interactions among researchers and users—to accelerate the capture of the benefits of research for Canadians through improved health, more effective services and products, and a strengthened health care system”. A prominent characteristic of KT is that it encompasses all steps between the creation of new knowledge and its application to yield beneficial outcomes for society. Essentially, KT is an interactive process underpinned by effective exchanges between researchers who create new knowledge and those who use it. KT can narrow the gaps between health research, health practice and health policy. KT concepts are universal and broadly applicable; yet teaching and learning about how to do effective KT has long been a challenge.

This introductory course in Knowledge Translation is designed to give students brief background knowledge in the importance of knowledge  translation in their research, prominent knowledge translation theories and models, strategies and measures to support research use in various fields and the importance of multi-faceted KT approaches. Our approach to KT is rooted in theory and science, but our application of KT is uniquely pragmatic and focused on real-world impact.

MSC1104H (0.25 FCE) Neurodegenerative Disease (Credit/No Credit) - Session: Winter 2022

Instructor: Carmela Tartaglia, Filsy Samuel; permission is required to enroll in this course.
Please send a brief statement of interest/background via email for enrollment approval.

Session Offered: 20221
Start Date: Tuesday, February 1st, 2022  (7 sessions), Time 4:00 - 6:00 pm, Location: tbd -- in person.

Description: A clinical and research overview of neurodegenerative diseases with a special focus on Alzheimer’s and Parkinson’s Disease. The module will provide students with a thorough understanding of clinical presentation, genetic and environmental causes, molecular underpinnings, and advances in therapeutic and biomarker research.

MSC1105H (0.25 FCE) Clinical Trials (Credit/No Credit) - Session: Winter 2022

Instructor: Peter Juni, Contact Information: Joanne Roberti

Session Offered: 20221
Dates:  February 16, 2022 - April 20, 2022 [Wednesdays], Time: 3:00 - 5:00 pm Location: Online

Description: To provide IMS students with an introduction to clinical trials.

MSC1106H (0.25 FCE) Respiratory Global Research and Training (GREAT) Network Epidemiology, Biostatistics and Surveillance Practicum (Credit/No Credit) - Session: Winter 2022

Instructor: Teresa To

Session Offered: 20221
Dates:  February - March 2022 (7 weeks), Location: Online Asynchronous 

Description: Each week over 7 weeks, basic concepts will be introduced in a 2-hour session at the GREAT Network SharePoint Server. To facilitate learning, exercises or tutorials will be given to trainees to work at their own time. You will be given instructions on attending the sessions via a log on user account and password. Course materials (reading materials, PowerPoint Presentations and handouts) will be downloadable from our SharePoint Server which will be opened for access to all participants after registration. To receive the certificate of completion, attendance of all 7 lectures is required. Each lecture will be opened to access for a week and participants can review the lecture at his/her own time and pace. At the end of each week’s lecture, participants are required to take a small quiz (comprises of about 5 multiple choice or short questions). Completion of the quiz is required to move forward to the next lecture.

MSC1107H (0.25 FCE) Biostatistics in a Nut Shell (Credit/No Credit) - Session:  Fall 2021

Instructor: Pascal Tyrell

Session Offered:  20219 F
Start Date: Wednesday, September 8th, 2021 (6 sessions, alternating weeks), Time 6:00 - 7:30 pm, Location: Online

Description: This short course is primarily for students in a MSc, PhD, or residency program that has a requirement of a data analysis. Students learn about important fundamental statistical principles by studying the analysis of real data.  Link to discussions:  http://www.tyrrell4innovation.ca/biostatistics-in-a-nutshell

MSC1108H (0.25 FCE): Animal Models of Human Diseases (Credit/No Credit) - Session:  Winter 2022

Instructor: Gaspard Montandon

Session Offered: 20221
Start Date: January 27, 2022, Time: 3-5 pm,  Location: In person

MSC1109H (0.25 FCE): Introduction to Neuroimaging (Credit/No Credit) - Session: tbd

Instructor: Ben Dunkley

Session Offered: tbd
Start Date: tbd, Location: tbd

Description: This module will provide a general survey of the major imaging modalities used in neuroimaging research. Several lecturers will talk about how these imaging methods have improved our understanding of various neurological disease conditions, with examples of where this has translated into improved clinical practice. We will review lesion studies, transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS), which all speak to the importance of understanding the spatial localization of brain function.

MSC1110H (0.25 FCE): Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21) (Credit/No Credit) - Session:  Fall 2021 - Winter 2022

Instructor: Shane Harding , C. Anne Koch 

Session Offered:  20219 - 20221 Y
Start Date: Tuesdays, October 12, 2021 - April 2022 (13 sessions, alternating weeks), Time: 5:30 pm - 7:00 pm,  Location: Online

Description:  The overall objective of this course is to develop an understanding of the transdisciplinary nature of radiation science both in practical clinical application and in research. This foundational knowledge will be built upon by placing radiation science in the context of the greater scientific enterprise academically and within society. 

Each interactive session is led by an expert in the topic who gives an introduction, followed by discussion or a group activity. 

 

Sessions include: 

  • Group presentations of trainee's projects 
  • Introduction to radiation biology, radiation oncology and physics for radiotherapy 
  • Science communication 
  • Knowledge translation 
  • Introduction to "Hot topics" in cancer research with a focus on radiation medicine (examples include personalized medicine, trial design, machine learning) 
  • Entrepreneurship 
  • Team science 
  • Career path

MSC1111H (0.25 FCE) Strategies for Systematic, Coping, or Other Comprehensive Searches of Literature (Credit/No Credit) - Session: tbd

Instructor: Mina Tadrous, Kaitlin Fuller

Session Offered: tbd
Date: Fridays, tbd, Time: tbd; Location: Online

Description: A systematic review of the literature is essential when conducting evidence-based research, especially in the health and life sciences. There is an increase in the number of systematic reviews, scoping reviews, or similar methodological reviews of the literature known as knowledge syntheses (KS) published each year. Learning outcomes for this module stress students’ critical understanding of the why, how and to what ends the search for a KS affects the overall quality of a review.

MSC1113H (0.25 FCE) Radiomics and Machine Learning in Medical Imaging (Credit/No Credit) - Session tbd

Instructor: Farzad Khalvati

Session Offered: tbd
Date: tbd, Time: tbd; Location: tbd

Description:  This is a 6-week modular course (0.25 FCE) designed to provide an understanding of fundamentals of Artificial Intelligence / Machine Learning (AI/ML) for wide applications in medical imaging. Medical Imaging, which is an important specialty in medicine for diagnosis, prognosis, and intervention of different types of diseases including cancer, is increasingly moving toward quantitative approaches. AI/ML algorithms are playing a key role in quantitative medical imaging analytics for disease diagnosis (detection) and prognosis (prediction). With the help of recent advances in AI/ML and computer vision, novel predictive models are capable of diagnosing a disease with high accuracy and consistency, and predicting clinical outcomes (e.g., response to treatment) with an accuracy, which is beyond existing clinical methods.

MSC1114H (0.25 FCE) Artificial Intelligence in Medicine (Credit/No Credit) - NEW Course - Session:  Fall 2021

Instructor: Pascal Tyrell

Session Offered:  20219 F
Start Date: Wednesday, September 15th, 2021  (6 sessions, alternating weeks), Time 6:00 - 7:30 pm, Location: Online

Description:  Artificial Intelligence (AI) is a rapidly developing field and has been revolutionizing the medical field to benefit medicine. This course uses recent literature, papers, and examples to look at the applications of AI tools to see how they can directly assist patients and medical professionals. This 0.25 FCE course is primarily for students in a MSc or PhD program that would like to gain insight on the emerging field. Some topics discussed include challenges in the medical field and how AI can help, applications of AI/ML, and future of AI in medicine

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MSC1115H (0.25 FCE) Digital Imaging for Cellular Microscopy (Credit/No Credit) - NEW Course - Session:  Winter 2022

Instructor: tbd

Session Offered: 20221 

Start Date: Jan. 12, 2022 to Feb. 16, 2022 (Wednesdays), Time 2:00 - 4:00 pm, Location: tbd (In person)

Description:  Each of the 6 sessions will consist of a theoretical component and a hands on component using sample data sets to facilitate the development of adequate image manipulation and analysis skills.

Enrollment Instructions: Permission is required to enroll in this course. Please email caterina.diciano-oliveira@unityhealth.to and copy cc.medscience@utoronto.ca

MSC1001Y: Human Anatomy - Session: Fall 2021

Instructor: Anne Agur
Please contact instructor for permission to register and course information. Please copy cc.medscience@utoronto.ca in your email.

Session Offered: 20219 F
Start date:  Tuesday, September 7th, 2021, Days/Times: Tues. 10:00 a m - 12 noon and 1:00 pm - 4:00 pm, Thurs. 9:00 am - 12:00 noon, Location: tbd.

Description: Gross anatomy of the human body taught from a regional viewpoint. The course is dissection based and includes interactive tutorials and dissection laboratories (96 hours). Anatomical structure and function is emphasized.  Social distancing measures will be followed. Method of course delivery may be subject to change. 

Enrollment Restrictions: Course enrollment is limited to 2 students enrolled in the School of Graduate Studies.

MSC1004H: Health and Pharmaceuticals (NEW Course) - Session: Fall 2021

Instructor: Nancy Olivieri

Session Offered: 20219 F
Start Date:  September 15th,  2021, Time: 2:30 pm - 5:00 pm, Location: Online

Description: A critical examination of drug development, including the role of health professionals and the pharmaceutical industry in researching, testing, marketing, licensing, and evaluating pharmaceutical drugs. Topics include the differing needs for drug development, evaluation and dispensing in lower income countries, and potential conflicts of interest in drug development.

MSC1006H: Neuroanatomy - Introduction to Anatomical Organization of the Brain - Not Offered in 2021-2022

Instructor: Mojgan Hodaie
Please contact instructor for permission to register and copy cc.medscience@utoronto.ca in your email.

Session Offered: Not offered in 2021-2022

Start Date: n/a, Time: n/a, Location: n/a

Description: This course will focus on detailed review of the fundamental organization of the nervous system, at both the gross and cellular levels. The major components of the nervous system will be discussed in a lecture format. The lectures will be supplemented with interactive anatomy sessions, either in the laboratory or using multimedia platforms. Student-led presentations will maximize the students’ contact with techniques employed to study neuroanatomy. This course is suitable for students who have some background in the neurosciences who are now embarking in a neuroscience project as part of their graduate degree. Course assessment will be based on quizzes, presentations as well as a final examination. Textbook: Neuroanatomy, text and atlas, by John H. Martin, 4th edition.

Prerequisites: Basic knowledge of mammalian neuroanatomy and permission of the instructor. Maximum enrollment of 18 students. Preference will be given to IMS students.

MSC1008H: Advanced Human Embryology and Teratology - Session Offered: Winter 2022

Course Director: Dr. Ted Brown

Please contact the Course Director to obtain the required permission prior to completing an ADD/DROP form.

Session Offered: 20221 S
Start Date: Monday, January 10th, 2022.  Lectures: Mondays 1-3pm, Fridays 1-3pm (in-person, room TBD). Tutorials: select Mondays 3-5pm (in-person, room TBD)

Prerequisites: Interested graduate students must have taken a previous undergraduate course in cell biology. 

Description: Human embryology from fertilization to the end of the fetal period. Topics include: current concepts in mammalian morphogenesis applied to the development of various organ systems; the principles of teratology; mechanisms of malformation and the etiology and pathogenesis of some of the more common human congenital abnormalities. Prerequisites: Interested graduate students must have taken a previous undergraduate course in cell biology. Enrollment 

Enrollment Restrictions: Limited to 5 graduate students, with an additional 5  spots reserved for the Clinical Embriology LMP program.

MSC1010H/Y & 1011Y/H: MSc/PhD Student Seminars in Translational Research - Session: Fall 2021 - Winter 2022

Course Director: Marianne Koritzinsky

Session Offered: 20219- 20221 Y
Lecture Start Date: Wednesday, September 15th - December 3rd, 20219, Time: 10:00 am – 12:00 noon, Location: Online

For more information on the MSC1010H/Y and MSC1011H/Y course click here.

MSC1030H: Learning from Data – Introduction to Study Design and Statistical Analysis Methods (NEW Course) - Session: Fall 2021

Instructor: Tony Panzarella

Session Offered: 20219 F
Start Date: Tuesday,  September 14th,  2021 (corrected start date), Time: 2:00 pm - 4:00 pm, Location: Online

Description: The goals of this course are to provide students with the ability to understand and interpret statistics to enable them to conduct their own research and to critically appraise research evidence from the scientific and medical literature.

To enable these goals, a “problem-driven” approach referred to by the acronym PPDAC* (Problem, Plan, Data, Analysis and Conclusion) will be used :

  1. outlining a problem and defining a research question to help solve this problem
  2. carefully planning a research study to answer the question reliably
  3. collecting the necessary data, and managing it appropriately to ensure it is of high quality
  4. analyzing the study results using statistical methods consistent with the type of data collected
  5. providing conclusions that reflect the results from the analysis

MSC1040H: Physiologic Basis of Disease: Bench to Bedside - Session: tbd

Instructor: Andrea McCart

Session Offered: tbd 

Description: This is a half-year lecture course designed for M.Sc. and Ph.D. students in the IMS who wish to gain an in-depth understanding of the basic mechanisms of disease, how these processes lead to the clinical syndromes and how medical research in these areas leads to effective therapy.

The aim of the course is to integrate basic molecular, cellular, or physiological processes with subsequent disease processes and their treatments. The course will provide an opportunity to gain insights into medical and surgical diseases from birth to adulthood. The latest research including clinical trials if applicable will be discussed. Topics that may be discussed include cancer, transplantation, diabetes, sepsis, epilepsy, inflammatory bowel disease and others. Papers of relevance to the discussion will be provided.

The course will consist of 12 2-hour sessions. Each session will feature a 1 hour lecture by faculty members of the University of Toronto who are authorities on the topic under discussion. This will be followed by the presentation of a related and relevant paper by 1-4 students (depending on enrolment) who will also lead the subsequent class discussion. Students will sign up for their presentations prior to the first class. Students will work with the respective faculty member to elect the paper for presentation.

MSC1081H: Studies in Schizophrenia - Session: Winter 2022

Instructor: George Foussias, Mahavir Agarwal

Session Offered: 20221 S
Start date: January 2022, Day/Time: tbd, Location: tbd

Description: This course, consisting of a series of readings, seminars, and a term paper, is intended to provide an in-depth and multidimensional understanding of schizophrenia spectrum disorders. Readings and seminars will include both foundational perspectives and recent advances in knowledge, bringing together the complexity of specialized knowledge that is required to carry out good research in the area of schizophrenia.

Topics included are:
• Introduction to course. What is Schizophrenia
• Signs and symptoms
• Prodrome and First episode Schizophrenia. Early detection
• Sociocultural aspects and vulnerable populations
• Neuropsychology
• Genetics
• Neuroimaging
• Neurophysiology
• Pharmacotherapeutics
• Animal models
• Research Ethics
• Overview and feedback

Enrollment Restrictions: Class size restricted to 20 students. Preference will be given to IMS students. If you are not an IMS student and wish to register for this course, please email the course instructors and copy cc.medscience@utoronto.ca

Prerequisites: The course has been designed for Masters and Ph.D. students in neuroscience, psychology and the social sciences. Knowledge of how the brain works is required.

MSC1085H: Molecular Approaches to Mental Health and Addictions - Session: tbd

Instructor: Robert Levitan, Daniel Mueller

Session Offered: tbd
Start Date:  tbd, Time:  tbd, Location: Online

Description: This popular course investigates the neuroscience knowledge and research strategies underlying major psychiatric disorders and related psychopharmacological treatment. Lectures will discuss insights gained from areas of research such as genomics, neuroimaging, pharmacology, animal models and bioethics. Particular attention will be paid to how these studies have refined our understanding of clinical phenomena.

Selected faculty members with particular expertise will deliver a lecture describing their research work, including an introduction to their field, major methodological issues and key discoveries. Ample time will be dedicated to interaction and discussion. The assignments consist of: 1) selecting a topic for a review article and providing an abstract, 2) presenting a brief oral presentation, and 3) submitting a review article (2,500 – 5,000 words) at the end of the course.  Each assignment will be reviewed by two faculty members who will generate a consensus grade.

Prerequisites: None, but a background in neuroscience, molecular biology, genetics, statistics and neuroanatomy are recommended.

MSC1087H: MRI Neuroimaging Methods - Session: tbd

Instructors:  Sofia Chavez, Andrea Kassner

Session Offered: tbd
Start Date: tbd, Time tbd , Location: tbd.

Description: Over the last two decades, the study of human brain structure and function has come to rely on the latest developments in medical imaging technology, especially magnetic resonance imaging (MRI). This course will provide an understanding of the principles of magnetic resonance imaging and cover concepts of advanced MRI neuroimaging methods used for quantitative imaging. The course is primarily intended for students who will use quantitative MRI neuroimaging techniques in their own thesis projects, and need to have a solid understanding of the physical and mathematical principles behind these methods in order to acquire good data and analyze them appropriately

MSC1088H: Brain Positron Emission Tomography - Not Offered

Instructor: N/A

Session Offered: Not offered 

Description: Positron emission tomography (PET) has become an important tool for the early detection of disease, the understanding of basic molecular aspects of brain function and the evaluation of medical treatment. This course will build on a multidisciplinary team involving chemists, physicists, image scientists, computer scientists and clinician scientists currently investigating brain diseases such as schizophrenia, mood disorders, addictions, geriatrics and movement disorders.

The principal objectives of this course are to review the fundamental concepts of PET imaging and to convey an understanding of the opportunities that PET technology offers in brain research and drug development. Specific issues will be addressed in a perspective to answer basic research questions:

1) The chemistry of labelling compounds with short-lived positron-emitting radionuclides; 2) The design of PET radiopharmaceuticals – impact on interpretation of scanning data (e.g. position of labelling, metabolism, drugs vs. ligands); 3) PET instrumentation – how does a PET scanner or a cyclotron work (physics)?; 4) How PET data is analysed (kinetic modelling, image analysis); How PET can be used as a tool in brain research and drug development.

MSC1089H: The Biopsychosocial Basis of Mental Health and Addictive Disorders - Session: Winter 2022

Instructor: Tony George; Tel: (416) 535-8501, ext. 4544

Session Offered: 20221 S
Starting date:  tbd, Time:  tbd, Location: tbd

Description: Prof. George and colleagues will review the biopsychosocial basis of mental health and addictive disorders from the perspectives of etiology, pathophysiology, clinical phenomenology and diagnostics, genetics, neuroimaging, and treatment which have all contributed to our increasing understanding of psychiatric and substance use disorders from a biomedical (“disease”) concept. The role of stigma and recovery would also be discussed from a biobehavioural and social determinants of health perspective, to produce an integrated perspective on mental health and addictive disorders. The contemporary approach to treatment of these disorders would also be discussed which emphasizes biological, psychological and social policy and prevention perspectives.

Enrolment: Limited to 16 students. Pre-approval for this course is required. Please contact Tony George and copy cc.medscience@utoronto.ca.

MSC1090H: Introduction to Computational Biostatistics with R - Session: Fall 2021

Course Director: Erik Spence

Session Offered: 20219 F
Starting date: Tuesday, September 14th, 2021, Days/Times:  Tuesdays and Thursdays, 12:00 noon – 1:30 pm
Location: Online

Description: The goal of this class is to prepare graduate students to perform scientific data analysis. Successful students will learn how to use statistical inference tools to gain insight into their data, as well as be exposed to techniques and best practices to store, manage and analyze data.

Topics to be covered:

  • Introduction to programming with R,
  • Programming best practices,
  • Data structures,
  • Review of basic statistics,
  • Introduction to Machine Learning algorithms,
  • Visualization of data

Prerequisites: No programming experience is necessary.  A laptop will be required to do the assignments.

Structure: Twelve weeks, with two 1.5-hour lectures per week. Final grades will be based on weekly assignments. Passing mark: 70% of the final grade.

Grading Scheme: Most weeks students will be given a programming assignment, with a due date one week after. These assignments are designed to help absorb the course material.  There will be between 10 and 12 assignments. The average of the assignments will make up the grade. There is no in-person mid-term. To ensure a timely reporting of student grades, we will adhere to the following policy:

Homework may be submitted up to one week after the due date, at a penalty of 0.5 point per day, out of the 10 points for each homework. Deviations of this rule will only be considered, on a case-by-case basis, in exceptional circumstances.

MSC2010Y: Molecular Medicine in Human Genetic Disease (Full Year Course) - Session: Fall 2021 - Winter 2022

Instructor: Lucy Osborne
Pre-approval for this course is required. Please contact the instructor and copy cc.medscience@utoronto.ca.

Session Offered: 20219 - 20221 Y
Start date:  Wednesday, September 15th, 2021 Time:  3:00 pm to 5:00 pm, Location: Online

Description: This course should encourage students to develop an approach to the genetic analysis, investigation and treatment of human disease.

In the body of the course, a series of 16 lectures will cover background relevant to the study of human genetic disease as well as specific examples of human genetic disease research.

Introduction to molecular approaches: Students will be introduced to useful tools and concepts that enable the study of a wide spectrum of human diseases. These include such topics as: population identification and sample collection; genome scanning with subsequent linkage analysis; copy number variation analysis and the use of animal models.

Specific examples of human genetic disease research: Lecturers will be encouraged to discuss the basic clinical presentation and pathophysiology of the genetic disease that they study; the approach they take in their research; the molecular changes that occur and key findings. Each lecture will provide an eample of the application of molecular tools to the investigation of a specific human disease. Lecturers will be encouraged to provide weekly reading assignments in advance of the lecture and will usually provide their slides to the class for review.

Each student will be required to sit a short answer exam (Deember), prepare a Letter of Intent for a grant proposal that addresses a research topic in human genetic disease (Ferbruary) and give a 10-15 minute in-class slide presentation of a research paper assigned by the Course Director (March), and write a short News & Views type article about a paper or papers in the field of human genertic disease that have been published during the past caledar year.

MSC6000H: Special Topics, Reading Course - Sessions: Fall 2021 and Winter 20221

Instructor: Arranged by student through petition (see below)

Session Offered: 20219 F and 20221 S

Description: A reading course on topics of interest to one or more Faculty Members. Student(s) usually meet weekly to read, criticize and discuss current literature in the field and write essay assignments. Reading course topics may NOT be based on the student’s thesis topic, and the student supervisor may NOT serve as instructor of a reading course. It is the responsibility of the student and instructor to prepare a course outline, grading scheme, etc.

Prerequisites: Suitable background for area of study.

Enrollment Restrictions: Preference will be given to IMS students. Students are required to petition in order to take this course. Please download a Request for Reading/Research Course at the SGS Web Site. Complete the form and bring it to the IMS Office. We recommend that you provide as much information as possible on the proposed course content, grading, and reasons for requesting a reading course.

The IMS Graduate Coordinator will review and approve your enrolment in MSC6000H. Questions? Please contact the IMS Office.

MSC7000Y: Regenerative Medicine (Full Year Course) - Session: Fall 2021 - Winter 2022

Instructor: Sonya MacParland

Session Offered: 20219 - 20221 Y
Start Date:  Thursday, September 9th, 2020, Time:  9 am – 11 am, Location: Online

Description: MSC7000Y is a unique flagship course of wide interest to students with a health professional background (i.e. MDs, RNs, clinicians), and scientists across Canada. This course will provide students with an understanding of the science behind the field, the bio-processes, new and emerging technologies, the ethical and regulatory aspects of implementation and the academic/industry partnerships on which clinical success is likely to be based. Content is as follows:

BACKGROUND: ORGAN FAILURE
Heart, Lung, Liver, Kidney, Pancreas Failure including physiology, human impact, and cost and the implications for regenerative medicine

Current Approaches to Management of Organ Failure including transplant and non-transplant approaches

REGENERATIVE MEDICINE AND INNOVATIVE TECHNOLOGIES (MAIN FOCUS)

  • Stem Cells (ESC, iPS, MSC, Islet, Neural, Retinal, Marrow)
  • Gene Therapy
  • Biomarkers & Assays
  • Stem Cell Aging, Manufacturing, and Engineering
  • Tissue Engineering (Lab/Organ on a Chip)
  • CRISPR Genome Editing

CLINICAL APPLICATIONS OF REGENERATIVE MEDICINE

  • Immune Tolerance in Transplant
  • Burns and Skin Regeneration
  • Imaging and Nanotechnology in Regenerative Medicine
  • Translation of New Therapies from Bench to Bedside
  • Fundamentals of Clinical Trials Design
  • Evaluation of Health-Related Quality of Life
  • Cost-Effectiveness & Global Health Economics
  • Adoption of New Therapies

ETHICS AND SOCIETY

  • Research Ethics
  • Transplant Ethics
  • Quality of Life – Patient perspective
  • Regenerative Medicine Ethics
  • Public Opinion and the Media
  • Regulation of Regenerative Medicine in Canada
  • IP and Commercialization of Regenerative Medicine

JOURNAL CLUB

  • Selected articles relevant to regenerative medicine will be selected for group participation during the course.
  • This course forms a major part of a Training Program in Regenerative Medicine.

Enrollment Restrictions: Maximum enrollment of 20 students at the University of Toronto, 20 students affiliated through the Stem Cell Network (across Canada).

This course is available for graduate students from other universities. Non-U of T graduate students must enroll in this course through their home University using existing off-campus study agreements (CUGTA or OVGS) or a request for transfer credit. Please contact the Program Coordinator, Anna Cocco, for more details.

Enrollment: Interested students must first receive permission from the Course Director, Dr. Sonya MacParland to take the course prior to registering.   Interested students must e-mail Dr. Sonya MacParland and copy the Education Coordinator, Anna Cocco with the following information:

  • Your personal information (Name, University and Department, Student ID Number
  • Program and Year of Study (i.e. MSc, PhD, PDF)
  • Your Supervisor’s information (Name and e-mail address)
  • A brief description (200 words or less) on i) your interest in taking this course, and ii) the relation of your research project to regenerative medicine.

MSC4001H: Foundations in Resuscitation Science Research - Session Offered: Fall 2021 - Winter 2022

Instructor:  Ben Leung, Dakota Gustafson

Session Offered:  20219 - 20221 Y
Start date:  Monday, September 13th, 2021 Time:  4:30 pm to 6:30  pm, Location: Online

 Please note this half-course will follow an irregular meeting schedule:

September 13, 27
October 4, 18
November 1, 15, 29
January 10, 24
February 7, 28
March 14, 28
April 4

Description: This 0.5 credit course is aimed at enhanced understanding of the breadth of research in resuscitation science. It will provide students within disparate fields of research enquiry with the fundamentals of the discipline and provide a forum to discuss common areas of research interest, thereby further reinforcing a spirit of interdisciplinary research. Topics include bioethical issues particular to resuscitation research; health services research with high risk groups; outcomes research in critical illness; translational research in resuscitation and knowledge translation. From bench to bedside to curbside, students will gain a thorough understanding of the issues and concerns unique to the field of resuscitation sciences.

For more information visit the CPRS website at Collaborative Program in Resuscitation Sciences.

MSC3001H: Foundations in Musculoskeletal Science - Session: Fall 2021

Instructor: Boris Hinz

Session Offered: Fall 2021
Start Date: Wednesday, September 8th, 2021  (13 sessions), Time: 2:00 pm - 4:00 pm
Location: Dentistry Building, 124 Edwards Street 5th Floor, Room #504 (to be confirmed)

Description: This is a half-credit required course which will be counted, in most of the participating home programs/ home graduate units, towards students’ home degree electives.   Students, regardless of home graduate unit and prior learning, receives a common foundation of the topics and issues particularly relevant to designing and conducting research in the highly interdisciplinary realm of musculoskeletal science. Students will achieve an enhanced appreciation of the breadth and complexities of research in the field, and will be better able to discuss disparate topic areas of research, thereby, reinforcing a spirit of interdisciplinary research. The MSC3001H is offered over one term, and consists of a series of twelve two-hour lectures to cover topics spanning over Bones, Cartilage, and Muscles. Lecturers are experts in their respective topics drawn from graduate units and clinical departments associated with the Collaborative Program in Musculoskeletal Science.

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

Students who are enrolled in the Collaborative Specialization of Musculoskeletal Sciences (CSMS) program will have priority. For details, visit the Collaborative Program in Musculoskeletal Sciences 

SRM 3333Y/SRD4444Y: Master’s/PhD Seminar Series in Resuscitation Sciences

Instructor: Paul Dorian

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For more information visit the CPRS website at Collaborative Program in Resuscitation Sciences

SRM3335H/SRD4445H: Master’s / PhD Seminar Series in Musculoskeletal Sciences

Instructor: Various

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Collaborative Program in Musculoskeletal Sciences. Students must be enrolled in the CPMS to enroll.

JCV3060H: Advanced Research in Cardiovascular Sciences, Molecular Biology and Heart Signal Transduction

Instructor: Steffen-Sebastian Bolz

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Cardiovascular Sciences.

JCV3061H: Advanced Research in Cardiovascular Sciences, Hormones

Instructor: Carin Wittnich

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details,  see Cardiovascular Sciences.

JCV3062H: Advanced Research in Cardiovascular Sciences, Heart Function

Instructor: Carin Wittnich

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Cardiovascular Sciences.

 

JCV3063: Advanced Research in Cardiovascular Sciences, Vascular

Instructor: Scott Heximer

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Cardiovascular Sciences.

JCV3065 – Advanced Topics in Cardiovascular Science – Systems Biology

Instructor: Anthony Gramolini

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Cardiovascular Sciences.

JFK1120H: Selected Topics in Drug Development I

Instructor: M. Piquette-Miller

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Pharmacology & Toxicology

JFK1121H: Selected Topics in Drug Development II

Instructor: S. Wu and P. Lee

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Pharmacology & Toxicology

JPM1005Y: Behavioural Pharmacology

Instructor: L. Zawertailo (Offered in alternate years)

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Pharmacology & Toxicology

JNR1444: Fundamentals of Neurological Science

Instructor: James Eubanks

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Pharmacology & Toxicology

JYG1555H: Topics in Molecular and Cellular Neurobiology

Instructor: L-Y Wang

Collaborative Specialization: This course is offered as a Collaborative Specialization and is not an IMS course. 

For details, see Pharmacology & Toxicology