Agessandro Abrahao Jr.

Research Synopsis

Transcranial MR-guided focused ultrasound has been approved as a therapeutic alternative for treatment-resistant essential tremor. This noninvasive technique is being tested clinically as a drug delivery platform in amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, Parkinson’s disease and brain tumours, by safely and temporarily opening the blood-brain barrier in targeted brain regions. ​

In collaboration with the Centre of Excellence in Focused Ultrasound at Sunnybrook, Dr. Abrahao’s research aims to expand the clinical testing of MR-guided focused ultrasound to treat neurological diseases.

Dr. Abrahao’s research interests also include clinical trials and epidemiological studies of ALS and other neurodegenerative diseases. He is also interested in the development of biomarkers for motor neuron function using transcranial magnetic stimulation and motor unit count techniques.