Assistant Professor
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Associate Member
Tereza Martinu
Location
UHN-Toronto General Hospital
Research Interests
Lung, Transplantation, Animal Models, Surgical Research, Molecular & Cell Biology
Research Themes
Infection, Immunology
Accepting
MSc
Research Synopsis
Dr. Martinu’s research focuses on mechanisms of chronic lung allograft dysfunction (CLAD). CLAD is the main obstacle to long-term survival after lung transplantation and it remains an untreatable and poorly understood condition. Dr. Martinu studies the role of Th17, IL-17, and other related cells and molecules, as well as epithelial injury in the development of airway and lung parenchymal fibrosis in animal models of lung transplantation. Dr. Martinu also runs several translational human studies that assess CLAD mechanistic pathways in research samples obtained from lung transplant patients.