Associate Professor
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Full Member
Christoph Licht
Location
Hospital for Sick Children
Research Interests
Genetics, Proteomics, Molecular & Cell Biology
Research Themes
Infection, Immunology
Research Synopsis
Dr Christoph Licht has established a research program at The Hospital for Sick Children (SickKids) to understand the pathomechanism of complement-mediated kidney diseases (e.g. aHUS and MPGN/C3G).
His research has prominent translational aspects and involves clinical and basic research.
Components are:
- an international registry of patients with complement-mediated kidney diseases (www.kidcom.ca) including a biorepository as well as clinical (genetic and biochemical) tests for patients with aHUS and MPGN/C3G; and
- a research program in the SickKids Research Institute Cell Biology Program where he studies the complement-induced interactions of endothelial cells and platelets / neutrophils, as well as the molecular responses of endothelial cells to complement activation.
- In addition, he has a long-standing interest in chronic, proteinuria-mediated chronic kidney disease (CKD), particularly in Alport Syndrome.