Brian Feldman

Administrative Assistant: Zahrah Aldawood, zahrah.aldawood@sickkids.ca, (416) 813-7707

Research Synopsis

Dr. Feldman is a clinician scientist and rheumatologist. He holds a general rheumatology clinic, where he sees children with arthritis and other rheumatic complaints, and the childhood dermatomyositis clinic. 

Recognizing the challenges involved in the study of rare disease, Dr. Feldman has worked to improve the tools available to assist in this research. He has worked at developing and refining outcome measurement tools for use in clinical trials and in outcome studies. He has developed innovative methodologies for the study of new therapies (e.g. the Randomized Placebo Phase Design) and refined and tested powerful existing methods (e.g. Bayesian meta-analysis of n-of-1 randomized trials, and causal modeling for longitudinally collected observational data).  

Dr. Feldman has made contributions to the understanding of the prognosis and treatment of juvenile dermatomyositis, the cost-effective prevention of arthropathy in severe hemophilia, the course and outcome of systemic-onset juvenile idiopathic arthritis and juvenile SLE, and the role of fitness, exercise, diet supplementation and sleep in childhood chronic diseases including arthritis, myositis and fibromyalgia.