Associate Professor
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Associate Member
Augusto Zani
Location
Hospital for Sick Children
Research Interests
Children’s Health, Stem Cells, Gastrointestinal & Biliary, Lung
Research Themes
Regenerative Medicine, Development
Research Synopsis
Dr. Zani’s research is funded by the Canadian Institutes of Health Research and the SickKids Foundation, and focuses on the two neonatal surgical conditions with the highest mortality: congenital diaphragmatic hernia (CDH) and necrotizing enterocolitis (NEC). Dr. Zani has founded the RESPIRE program (Regeneration via Stem Cell Products for the Improvement of Respiration) and his lab is investigating strategies to regenerate fetal lungs using a stem cell based therapy for pulmonary hypoplasia secondary to CDH. Dr. Zani is also investigating the causes of brain damage and neurodevelopmental delay that occur in NEC survivors and the potential strategies that could be employed to prevent NEC associated morbidity.