Professor
|
Full Member
Aaron Schimmer
Location
UHN-Princess Margaret Cancer Centre
Research Interests
Cancer, Stem Cells, Animal Models
Research Themes
Cancer
Accepting
MSc, PhD
Research Synopsis: Chemical Biology and Drug Discovery
Our lab is interested in developing new therapeutic strategies for AML (acute myeloid leukemia) that effectively target leukemic stem cells. Using genetic and chemical approaches, including high throughput screens, we identify biological vulnerabilities in the AML cells and stem cells with a focus on mitochondrial and metabolic pathways. Through these efforts, we discover new biological pathways important for the growth and viability of AML and highlight new therapeutic approaches for this disease.