Rosanna Weksberg

Research Synopsis

Dr. Weksberg’s research is focused on elucidating the role of epigenetics in human disease. In particular the lab is interested in exploring the impact of genetic and environmental factors on epigenetic marks and their role in human growth and neurodevelopment. Recent work highlights the study of genome–wide epigenetic variation in different normal human tissues as well as in neurodevelopmental syndromes and growth disorders. Considerable effort has also, in recent years, been directed at defining the optimal experimental systems to use for the identification of epigenetic alterations associated with human disease. Specifically these have included evaluations of various cell types, genome-wide microarray platforms, validation techniques, and bioinformatics tools. Over 200 peer-reviewed papers have been published.