Michael Fehlings

Research Synopsis

My basic science laboratory integrates molecular, imaging, electrophysiological, and neurobehavioural approaches to examine the pathophysiology and treatment of traumatic and non-traumatic forms of spinal cord injury (SCI). Current studies in SCI are focused on understanding the mechanisms of the secondary injury after SCI with a focus on examining the role of inflammation, the development of novel neuroprotective strategies, and the use of stem cell transplantation to repair the injured spinal cord. The translation from benchside to bedside is a key goal of our research and is exemplified in the team's involvement in clinical trials. Additionally, my laboratory has a vibrant clinical research program exploring machine learning (supervised and unsupervised learning), other AI analytic approaches, trajectory-based modeling, and advanced imaging to predict outcomes for individuals living with spinal cord injury and degenerative cervical myelopathy.